Plant Transcription Factor Database
Previous version: v3.0
Nicotiana benthamiana
E2F/DP Family
Species TF ID Description
Niben101Scf00801g04021.1E2F/DP family protein
Niben101Scf01357g00014.1E2F/DP family protein
Niben101Scf01359g03007.1E2F/DP family protein
Niben101Scf01372g01005.1E2F/DP family protein
Niben101Scf01750g15001.1E2F/DP family protein
Niben101Scf04654g04001.1E2F/DP family protein
Niben101Scf05411g02017.1E2F/DP family protein
Niben101Scf06280g02003.1E2F/DP family protein
Niben101Scf07162g03019.1E2F/DP family protein
Niben101Scf07370g01009.1E2F/DP family protein
Niben101Scf08034g00003.1E2F/DP family protein
Niben101Scf08259g02004.1E2F/DP family protein
Niben101Scf10018g00007.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710